Benztropine mesylate tablet US prescribing information. WebMD User Reviews should not be considered as medical advice and are not a substitute for professional medical advice, diagnosis, or treatment. Never delay or disregard seeking professional medical advice from your physician or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences may be a helpful health information resource but they are never a substitute for professional medical advice from a qualified healthcare provider.
Your pharmacist has more information about phenylephrine and promethazine written for health professionals that you may read. Some MEDICINES MAY INTERACT with Phenergan suppositories. It may also be used for a short time to treat a runny nose due to the common cold. If you experience increased constipation, drowsiness, dry mouth, dizziness, or blurred vision, contact your doctor. The suppository form is used when medications cannot be taken by mouth.
Nausea is minimal after usual oral doses of codeine. What Is Ischemic Heart Disease? Promethazine is an antihistamine. Wernicke's encephalopathy can cause confusion, lack of muscle coordination, and vision problems.
Regular medical checkups: During follow-up visits, your doctor will make sure you are staying healthy and that your heart disease is not getting worse. Hallucinations have also been reported. Deliberate self-administered drug overdose. Retrieved 27 November 2011. Avoid prolonged exposure to sunlight. Phenylephrine and promethazine may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.
Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking phenylephrine and promethazine. What Is Promethazine and How Does It Work? This medication can cause severe tissue damage, possibly requiring surgery. Tell your health care professional right away if you have burning, pain, redness, swelling, or numbness at or near the injection site. If this occurs, the injection should be stopped and the injection site checked. Do not start using a new medication without telling your doctor. CAUTION SHOULD BE EXERCISED WHEN ADMINISTERING PHENERGAN PROMETHAZINE HCL SUPPOSITORIES TO PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER BECAUSE OF THE POTENTIAL FOR FATAL RESPIRATORY DEPRESSION. RESPIRATORY DEPRESSION AND APNEA, SOMETIMES ASSOCIATED WITH DEATH, ARE STRONGLY ASSOCIATED WITH PROMETHAZINE PRODUCTS AND ARE NOT DIRECTLY RELATED TO INDIVIDUALIZED WEIGHT-BASED DOSING, WHICH MIGHT OTHERWISE PERMIT SAFE ADMINISTRATION. CONCOMITANT ADMINISTRATION OF PROMETHAZINE PRODUCTS WITH OTHER RESPIRATORY DEPRESSANTS HAS AN ASSOCIATION WITH RESPIRATORY DEPRESSION, AND SOMETIMES DEATH, IN PEDIATRIC PATIENTS. Wash your hands before and after using Phenergan suppositories. If the suppository is too soft to use, put it in the refrigerator for about 15 minutes. You may also run cold water over it. Remove the wrapper. Moisten the suppository with cool water. Lie down on your side. Insert the pointed end of the suppository into the rectum. Use your finger to push it in completely. Administration of promethazine has been associated with reported cholestatic jaundice. This medication may make you sweat less, making you more likely to get heat stroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using hot tubs. When the weather is hot, drink a lot of fluids and dress lightly. If you overheat, quickly look for a place to cool down and rest. As medication to combat etc. Like the persons name may have been there. But not the mg or g of the med. How many pills were in the orig Rx, what date it was filled, then they could have done the math on that. Drug information contained herein may be time sensitive. This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Avoid alcoholic beverages. Children should be supervised during bicycle riding and other possibly hazardous activities to avoid injury.
Patients should be advised to report any involuntary muscle movements. The dosage is based on your age, medical condition, and response to treatment. If you are using the chewable tablets, chew each tablet well and swallow. If you are using the dissolving strips, allow each strip to dissolve on the and then swallow, with or without water. Talk to your doctor or about lifestyle changes that might benefit you. For Product Inquiry call 1-877-845-0689. Treatment of overdosage is essentially symptomatic and supportive. Only in cases of extreme overdosage or individual sensitivity do vital signs, including respiration, pulse, blood pressure, temperature, and EKG, need to be monitored. Attention should be given to the reestablishment of adequate respiratory exchange through provision of a patent airway and institution of assisted or controlled ventilation. Diazepam may be used to control convulsions. Acidosis and electrolyte losses should be corrected. Note that any depressant effects of PHENERGAN Injection are not reversed by naloxone. Phenergan Injection may be used alone or as an adjunct to narcotic analgesics during labor see . Limited data suggest that use of Phenergan Injection during labor and delivery does not have an appreciable effect on the duration of labor or delivery and does not increase the risk of need for intervention in the newborn. The effect on later growth and development of the newborn is unknown. The suppository is for rectal use only. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. In pediatric patients 2 years of age and older, the dosage should not exceed half that of the suggested adult dose. Do not take extra medicine to make up the missed dose. When administered intravenously, PHENERGAN Injection should be given in a concentration no greater than 25 mg per mL and at a rate not to exceed 25 mg per minute. It is preferable to inject through the tubing of an intravenous infusion set that is known to be functioning satisfactorily. glipizide
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Promethazine is listed as one of the drugs of highest anticholinergic activity in a study of anticholinergenic burden, including long-term cognitive impairment. Phenergan Promethazine HCl Suppositories are contraindicated in comatose states, and in individuals known to be hypersensitive or to have had an idiosyncratic reaction to promethazine or to other phenothiazines. This can be harmful to your baby. Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Migraines are a common type of headache that can cause severe pain, aura or flashes in vision, and tingling. Subsequent doses on succeeding days of travel should be given on rising and again before the evening meal. Use Phenergan suppositories with extreme caution in the ELDERLY; they may be more sensitive to its effects. Reye's syndrome. The use of Phenergan Injection should be avoided in pediatric patients whose signs and symptoms may suggest Reye's syndrome or other hepatic diseases. where can you furosemide answers furosemide
It may be necessary to discontinue or adjust the dose of one or both medicines. Promethazine hydrochloride is a phenothiazine derivative which possesses antihistaminic, sedative, antimotion-sickness, antiemetic, and anticholinergic effects. Promethazine is a competitive H 1 receptor antagonist, but does not block the release of histamine. Marilyn, then Michael Jackson. Celebrities should NOT be allowed to have private house call or live in doctors. BOTH had sleep issues. BOTH MJ at least is verified had their docs kill them. Phenergan Injection in doses of 50 mg will provide sedation and relieve apprehension in the early stages of labor. When labor is definitely established, 25 to 75 mg average dose, 50 mg Phenergan Injection may be given with an appropriately reduced dose of any desired narcotic see . If necessary, Phenergan Injection with a reduced dose of analgesic may be repeated once or twice at four-hour intervals in the course of a normal labor. A maximum total dose of 100 mg of PHENERGAN Injection may be administered during a 24-hour period to patients in labor. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely. If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. If you have any questions, ask your doctor or pharmacist. Symptoms of intoxication include euphoria, slowed reaction time, dizziness, confusion, numbness, and more.
What happens if I overdose Phenergan Vc? Neuroleptic malignant syndrome NMS is a possibly fatal syndrome that can be caused by Phenergan suppositories. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at once if you have any of these symptoms. What are the symptoms? Dundee JW. Chlorpromazine as an adjuvant in the relief of chronic pain. Ask your health care provider any questions you may have about how to use Phenergan. If you miss a dose of Phenergan suppositories and you are using it regularly, use it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not use 2 doses at once. price crixivan spc crixivan
Call for emergency services. Tetany is a mineral imbalance causing painful muscle cramps and twitches in the hands, feet, face, and larynx. How and by whom her death was first noticed, what quantity of which drugs, administered in what fashion and by whom, how she ended up dead in that bed in that room, who did what? Antiemetics are not recommended for treatment of uncomplicated vomiting in pediatric patients, and their use should be limited to prolonged vomiting of known etiology. If you are using Phenergan suppositories for motion sickness, take a dose at least 30 to 60 minutes before you begin traveling. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. What happens if I miss a dose? cheap tolterodine vaistai
Some of these products contain sulfites. Sulfites may cause an allergic reaction in some patients eg, asthma patients. Sedation in both children and adults, as well as relief of apprehension and production of light sleep from which the patient can be easily aroused. Diabetic neuropathy is a nerve condition of the extremities causing numbness, tingling, and pain. Do not stop taking any medications without consulting your healthcare provider. However, some women are ultra-rapid metabolizers of codeine. B6 in people who not get enough of the vitamin from their diets. Dupuytren's contracture is a condition of the hand tissue that causes the fingers to curl. Take phenylephrine and promethazine exactly as directed by your doctor. If you do not understand the directions on your prescription bottle, ask your pharmacist, nurse, or doctor to explain the instructions to you. It is also used to treat allergy symptoms such as rash, itching, and runny nose. Drug interactions, including an increased incidence of extrapyramidal effects, have been reported when some MAO Inhibitors and phenothiazines are used concomitantly. This possibility should be considered with Phenergan Injection. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Avoid analeptics, which may cause convulsions. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. It is not known whether phenylephrine and promethazine passes into breast milk. Do not take phenylephrine and promethazine without first talking to your doctor if you are breast-feeding a baby.
Adequate studies to determine the action of the drug on parturition, lactation and development of the animal neonate have not been conducted. Adverse reactions include burning, pain, thrombophlebitis, tissue necrosis, and gangrene. Children may also experience excitability rather than drowsiness. Barbiturates are a type of prescription sedative in which even a slight overdose can cause coma or death. Phenergan is to be used only by the patient for whom it is prescribed. Do not share it with other people. Due to the risks of intravenous injection, the preferred route of administration of Phenergan Injection is deep intramuscular injection. Subcutaneous injection is contraindicated. See for important notes on administration. These may help reduce the pain or the number of migraines you have. Good thing is these drugs are rarely used outside hospitals now. Only on very rare occasions as ur body builds a tolerance requiring more to get desired effect. If your symptoms do not improve or if they become worse, check with your doctor. Check the labels of all your medications to make sure you are not taking more than one product containing dextromethorphan. Dizziness, drowsiness, and confusion can increase the risk of falling. store sotalol tablet
Children may be more sensitive to the side effects of this drug, especially slowed breathing see Warning section. This drug can often cause excitement in young children instead of drowsiness. Special care should be taken when using this medication in children who have lost a lot of fluid dehydration those who have a family history of sudden infant death syndrome SIDS and those who are hard to wake up from sleep. It also has a drying effect. Antihistamines are contraindicated for use in the treatment of lower respiratory tract symptoms including asthma. American Journal of Health-System Pharmacy. Antiemetic therapy in postoperative patients. Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Diazepam may be used to control convulsions. Stimulation may be evident, especially in children and geriatric patients. Convulsions may rarely occur. A paradoxical-type reaction has been reported in children receiving single doses of 75 mg to 125 mg orally, characterized by hyperexcitability and nightmares. Allergic conjunctivitis due to inhalant allergens and foods. Specific studies to test the action of the drug on parturition, lactation, and development of the animal neonate were not done, but a general preliminary study in rats indicated no effect on these parameters. Although antihistamines have been found to produce fetal mortality in rodents, the pharmacological effects of histamine in the rodent do not parallel those in man. There are no adequate and well-controlled studies of Phenergan Promethazine HCl Suppositories in pregnant women. The median nerve, which runs through the arm and hand, can cause swelling pain and numbness if injured. Long-term animal studies have not been performed to assess the carcinogenic potential of promethazine, nor are there other animal or human data concerning carcinogenicity, mutagenicity, or impairment of fertility with this drug. Promethazine was nonmutagenic in the Salmonella test system of Ames. ANTIEMETICS ARE NOT RECOMMENDED FOR TREATMENT OF UNCOMPLICATED VOMITING IN PEDIATRIC PATIENTS, AND THEIR USE SHOULD BE LIMITED TO PROLONGED VOMITING OF KNOWN ETIOLOGY. See USP Controlled Room Temperature. Anaphylactic reactions, as adjunctive therapy to epinephrine and other standard measures, after the acute manifestations have been controlled. As an adjunct to preoperative or postoperative medication, 25 to 50 mg of Phenergan Injection in adults may be combined with appropriately reduced doses of analgesics and atropine-like drugs as desired. ihho.info sotalol
Hyperexcitability and abnormal movements have been reported in patients following a single administration of promethazine HCl. Consideration should be given to the discontinuation of promethazine HCl and to the use of other drugs if these reactions occur. Respiratory depression, nightmares, delirium, and agitated behavior have also been reported in some of these patients. Drugs other than those listed here may also interact with phenylephrine and promethazine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products. Paxil paroxetine hydrochloride US prescribing information. If you are using Phenergan for motion sickness, take a dose at least 30 to 60 minutes before you begin traveling. Caution should be exercised when administering Phenergan Injection to pediatric patients 2 years of age and older. It is recommended that the lowest effective dose of PHENERGAN Injection be used in pediatric patients 2 years of age and older. Avoid concomitant administration of other drugs with respiratory depressant effects because of an association with respiratory depression, and sometimes death, in pediatric patients.
Continued How are they treated? This medicine may be harmful if swallowed. Phenergan is a registered trademark of Wyeth and is used under license. Burns caused by heat are called thermal burns and can cause pain swelling, skin changes, blisters and more. Phenergan suppositories should not be used in CHILDREN younger than 2 years old. Serious, and sometimes fatal, side effects difficult or slowed breathing, drowsiness leading to coma have occurred when Phenergan suppositories has been used in children in this age group. buy cafergot online uk
Drowsiness is the most prominent CNS effect of this drug. Sedation, somnolence, blurred vision, dizziness; confusion, disorientation, and extrapyramidal symptoms such as oculogyric crisis, torticollis, and tongue protrusion; lassitude, tinnitus, incoordination, fatigue, euphoria, nervousness, diplopia, insomnia, tremors, convulsive seizures, excitation, catatonic-like states, hysteria. Hallucinations have also been reported. How closely connected were the mob and the CIA? High serotonin levels may cause changes in body temperature, blood pressure, muscle movements and mood, leading to a medical condition called Serotonin Syndrome. Serotonin Syndrome may be very serious or rarely life threatening. When Marilyn Monroe was found dead, it was stated as an accidental suicide. Phenergan Injection can cause severe chemical irritation and damage to tissues regardless of the route of administration. Irritation and damage can result from perivascular extravasation, unintentional intra-arterial injection, and intraneuronal or perineuronal infiltration. Adverse reactions include burning, pain, thrombophlebitis, tissue necrosis, and gangrene. HEDIS Measure: . In many countries including the US and UK promethazine is contraindicated in children less than two years of age, and strongly cautioned against in children between two and six, due to problems with respiratory depression and sleep apnea. Take the medicine pack with you. CREST syndrome is a rare autoimmune disease that causes tissues to harden throughout the body. Store at room temperature away from light and moisture. not store in the bathroom. Do not freeze. Different brands of this have different storage needs. This means that the heart muscle isn't getting enough blood. Ischemic heart disease is usually the result of or hardening of the which impedes blood flow to the heart. Phenothiazines may cause hypotension including orthostatic hypotension reflex tachycardia, increased pulse rate, syncope, and dizziness, particularly after the first parenteral dose but rarely after the first oral dose. Low-potency agents such as chlorpromazine and thioridazine are more likely to induce these effects, which usually subside within the first couple of hours following administration. Tolerance to the hypotensive effects often develops after a few doses. Rarely, fatal cardiac arrest has occurred secondary to severe hypotension. Other reported adverse cardiovascular effects include edema, thrombosis, and ECG abnormalities such as PR and QT interval prolongation, diffuse T-wave flattening, and ST segment depression. Therapy with phenothiazines should be avoided or otherwise administered cautiously in patients with severe cardiovascular disease, pheochromocytoma, a predisposition to hypotension, or conditions that could be exacerbated by hypotension such as a history of myocardial infarction, angina, or ischemic stroke. Close monitoring of cardiovascular status, including ECG changes, is recommended at all dosages. If parenteral therapy is given, patients should be in a supine position during administration and for at least 30 to 60 minutes afterwards. Patients who experience orthostatic hypotension should be cautioned not to rise too abruptly. Occasionally, when severe, hypotension may require treatment with vasoconstrictive agents such as norepinephrine or phenylephrine. Epinephrine should not be used, however, since phenothiazines can reverse its vasopressor effects and cause a further lowering of blood pressure. Who was behind the assassination of JFK? Therefore, this product is not recommended to treat in children younger than 6 years. Signs and symptoms of overdosage range from mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes Babinski reflex. Ask your health care provider any questions you may have about how to use Phenergan suppositories. CYP2D6 or high morphine concentrations. acticin
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An intracranial hematoma occurs after a head injury and causes headache, drowsiness, confusion, and more. For other uncomplicated allergic conditions of the immediate type when oral therapy is impossible or contraindicated. Clinical effects are generally apparent within 5 minutes of an intravenous injection and within 20 minutes of an intramuscular injection. Duration of action is four to six hours, although effects may persist up to 12 hours. Promethazine hydrochloride is metabolized in the liver, with the sulfoxides of promethazine and N-desmethylpromethazine being the predominant metabolites appearing in the urine. Following intravenous administration in healthy volunteers, the plasma half-life for promethazine has been reported to range from 9 to 16 hours.
If the first medicine doesn't work, ask your doctor if you can try something else. It may take time to find what works best for you. Nonteratogenic Effects Phenergan Promethazine HCl Suppositories administered to a pregnant woman within two weeks of delivery may inhibit platelet aggregation in the newborn. Do not take this medication for several days before because test results can be affected. Some medical conditions may interact with Phenergan. When using this medication in children 2 years and older, use the lowest effective dosage and avoid other drugs that affect breathing.
Side Effects List Promethazine HCL side effects by likelihood and severity. Antibiotics can cause stomach pain, diarrhea, nausea, vomiting, itching, rashes and dizziness. Benzodiazepines are prescription medications that cause drowsiness, dizziness, blurred vision, and more. What Is Heart Failure? It does appear to be clear that a defect in the receptors to dopamine dopamine D2 receptor antagonism is an important contributor to the cause of neuroleptic malignant syndrome.
Keep track of how much of this medicine has been used. The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your not to work correctly. These are possible, but not always occur. Your doctor or can often prevent or manage interactions by changing how you use your medications or by close monitoring. Active and prophylactic treatment of motion sickness.